Molecular Karyotyping
Array-based comparative genomic hybridization (CGH) is a molecular technique that allows detection of chromosomal copy number changes at a genome-wide and high-resolution scale. With the array-based CGH technique, it is possible to investigate in more detail the chromosomal anomalies that cannot be diagnosed by cytogenetic methods.
This method provides a serious diagnosis opportunity together with chromosome analysis in elucidating the etiology of multiple congenital anomalies detected by fetal US during pregnancy. It also gives this opportunity for studies made from abortion material. It is possible to illuminate the etiology of intellectual disability and autism spectrum disorder with this method. The test result can be obtained within 10-20 days.